What is the primary response of neutrophils during an infection?

• A. To create antibodies
• B. To release histamine
• C. To phagocytize and destroy pathogens
• D. To promote muscle contraction

Answer: (C)

Neutrophils play a crucial role as the first line of defense in the immune response during an infection. Their primary response involves phagocytosis, a process in which they engulf and digest pathogens such as bacteria and fungi. Once the neutrophils arrive at the site of infection, they employ various mechanisms to recognize, internalize, and destroy these foreign invaders. They are equipped with enzymes and reactive oxygen species that help break down the pathogens once they are enclosed within a phagosome.

While creating antibodies is a function of B cells and the adaptive immune system, releasing histamine is associated with mast cells and basophils, which are involved in allergic responses and inflammation. Promoting muscle contraction is not a function of neutrophils; rather, it is related to the actions of different cell types in the body, such as muscle fibers and some neurons. Therefore, the primary and critical function of neutrophils during infection is to phagocytize and destroy pathogens, making them vital for acute inflammatory responses and initial immune defense.